Chronic pain is a reality for many, but it often does not indicate that the body is “damaged.” Instead, it may be a sign that our internal alarm system has become more sensitised.
In our clinic, we approach pain in an integrated way, using Physiotherapy, Osteopathy, and Psychoneuroimmunology (PNI), recognising that persistent pain often results from the interaction between our biology and modern lifestyle habits.
EVOLUTIONARY MISMATCH
The human body was designed to move, to face short periods of hunger and thirst, and to tolerate variations in temperature. However, today we live in an environment of increased comfort, often characterised by sedentary behaviour and a diet rich in ultra-processed foods.
This reality may contribute to a condition known as Low-Grade Inflammation (LGI), a silent form of inflammation that keeps the immune system in a constant state of alert, potentially interfering with natural recovery processes.
WHY DOES PAIN PERSIST?
For inflammation to resolve, the body requires “stop signals,” known as resolomics. When lifestyle includes chronic stress, lack of sleep, and a diet high in inflammatory fats (such as excessive omega-6, for example), the body may have greater difficulty producing these signals.
As a result, pain may stop being just a symptom and become part of a persistent condition.
PATHWAYS TO RECOVERY
Recovery from chronic pain goes beyond treating the affected area. It is important to approach the body in an integrated way, considering metabolism, the nervous system, and the individual’s life context.
One of the first steps is movement. Sedentary behaviour is a factor associated with persistent pain, so regular physical activity can be a relevant strategy. In some cases, exercising in a fasted state may be considered, provided it is adapted to the individual context.
This type of stimulus may contribute to the regulation of inflammatory processes and to overall well-being.
In addition, nutrition plays a fundamental role.
Maintaining an appropriate balance between omega-3 and omega-6 is important for regulating inflammation and supporting overall health. A nutrient-rich diet can contribute to a better physiological response.
Finally, hormesis - which refers to exposure to small challenges - may also be considered. Controlled exposure to stimuli such as cold, heat, or other physical challenges can support the body’s adaptive capacity when appropriately integrated.
Taken together, these strategies may contribute to a more comprehensive approach to pain and lifestyle.
CLINICAL APPROACH
In our clinic, we offer a personalised approach to each patient, starting with a thorough assessment that guides the treatment plan. We combine manual therapy to help reorganise tissues with a deep learning approach, supporting the understanding of pain biology.
This combination of methods allows the brain to stop interpreting pain as a constant threat, promoting a healthier and more balanced recovery process.
FINAL NOTE
The content presented here is for informational purposes and does not replace an individual assessment by a healthcare professional.
An appropriate approach, based on understanding the context and integrating different strategies, can contribute to more effective pain management and the promotion of a more balanced lifestyle.
Paula Almeida
Physiotherapist
references
Bosma-den Boer, M. M., van Wetten, M. L., & Pruimboom, L. (2012). Chronic inflammatory diseases are stimulated by current lifestyle: how diet, stress levels and medication prevent our body from recovering. Nutrition & Metabolism, 9(1), 32.
Cordain, L., Eaton, S. B., Sebastian, A., et al. (2005). Origins and evolution of the Western diet: health implications for the 21st century. The American Journal of Clinical Nutrition, 81(2), 341-354.
Nesse, R. M., & Williams, G. C. (1994). Why We Get Sick: The New Science of Darwinian Medicine. Times Books.
Ruiz-Núñez, B., Pruimboom, L., Dijck-Brouwer, D. J., & Muskiet, F. A. J. (2013). Lifestyle and nutritional imbalances associated with Western diseases: causes and consequences of chronic systemic low-grade inflammation in an evolutionary context. The Journal of Nutritional Biochemistry, 24(7), 1183-1201.
Serhan, C. N., & Levy, B. D. (2018). Resolvins in inflammation: emergence of the pro-resolving superfamily of mediators. The Journal of Clinical Investigation, 128(7), 2657-2669.
Serhan, C. N. (2014). Pro-resolving lipid mediators are leads for resolution physiology. Nature, 510(7503), 92-101.
Ji, R. R., Xu, Z. Z., Strichartz, G., & Serhan, C. N. (2011). Emerging roles of resolvins in the resolution of inflammation and pain. Trends in Neurosciences, 34(11), 599-609.
Pedersen, B. K. (2011). Muscles and their myokines. Journal of Experimental Biology, 214(2), 337-346.
Pruimboom, L. (2011). Physical inactivity is a disease synonymous for a non-permissive brain disorder. Medical Hypotheses, 77(5), 708-713.
Pruimboom, L., Raison, C. L., & Muskiet, F. A. J. (2015). Physical activity protects the human brain against metabolic stress induced by a postprandial and chronic inflammation. Behavioural Neurology, 2015.
Mattson, M. P. (2008). Hormesis defined. Ageing Research Reviews, 7(1), 1-7.
Pruimboom, L., & Muskiet, F. A. J. (2018). Intermittent living; the use of ancient challenges as a vaccine against the deleterious effects of modern life – A hypothesis. Medical Hypotheses, 120, 28-42.